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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5J All Species: 3.94
Human Site: S290 Identified Species: 9.63
UniProt: Q15735 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15735 NP_001002837.1 1006 107197 S290 A R P E A L H S S P E D P V L
Chimpanzee Pan troglodytes A0FI79 644 70203
Rhesus Macaque Macaca mulatta XP_001110784 811 87406 V167 S P N R S P C V P P A P D M A
Dog Lupus familis XP_543486 1008 107177 S292 A R P E A P R S S P E D P V L
Cat Felis silvestris
Mouse Mus musculus P59644 1003 107585 H291 A R P E A P R H S P E D P V L
Rat Rattus norvegicus Q9JMC1 1001 107190 H291 A R P E A P R H S P E D P V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507443 768 84124 D124 A S P T S S P D G A A P G G R
Chicken Gallus gallus XP_415287 1011 110631 P302 N V G T A M P P N D V T S L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698057 784 85922 P140 G F N P P S I P P T L P S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780987 442 50512
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.8 78.9 87.5 N.A. 82.2 83.9 N.A. 56.2 42.2 N.A. 40.8 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 32.3 79.4 91.5 N.A. 86.7 88 N.A. 63.6 55.3 N.A. 51.1 N.A. N.A. N.A. N.A. 29.3
P-Site Identity: 100 0 6.6 86.6 N.A. 80 80 N.A. 13.3 13.3 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 0 26.6 86.6 N.A. 80 80 N.A. 20 33.3 N.A. 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 50 0 0 0 0 10 20 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 10 0 40 10 0 0 % D
% Glu: 0 0 0 40 0 0 0 0 0 0 40 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 10 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 10 20 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 10 0 0 10 50 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 0 20 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 50 10 10 40 20 20 20 50 0 30 40 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 40 0 10 0 0 30 0 0 0 0 0 0 0 10 % R
% Ser: 10 10 0 0 20 20 0 20 40 0 0 0 20 0 0 % S
% Thr: 0 0 0 20 0 0 0 0 0 10 0 10 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 10 0 0 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _